A new antibiotic,, asukamycin, produced by Streptomyces.

نویسندگان

  • S Omura
  • C Kitao
  • H Tanaka
  • R Oiwa
  • Y Takahashi
چکیده

Asukamycin, a new antibiotic, has been isolated from the culture broth of a streptomycete designated as Streptomyces nodosus subsp. asukaensis. The antibiotic inhibits the growth of Gram-positive bacteria including Nocardia asteroides. The empirical formula of antibiotic asukamycin has been proposed as C29H22N2O9 (M.W. 542). An acute toxicity of the antibiotic in mice is LD50 48.5 mg/kg by intraperitoneal injection and it has no effect on mice when it was administered by 450 mg/kg per os.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 29 9  شماره 

صفحات  -

تاریخ انتشار 1976